USMLE provides an outline of the USMLE Step 1 Content. The outline breaks down the exam into systems.  This page will review the blood and lymphoreticular system section of the USMLE Step 1 outline as it relates to pharmacology.

Blood and Lymphoreticular System

Here is a look at a summary of USMLE outline for the blood and lymphoreticular system section with a focus on pharmacology related topics.

Parasitic Infections: Treatments/mechanisms
  • Bubonic plague, cat-scratch disease
Hemoglobin/heme Conditions
  • Iron-deficiency anemia
  • Methemoglobinemia
  • Sideroblastic anemia (Lead poisoning, isoniazid, copper deficiency)
Sickle Cell Disease
Coagulation Disorders
  • Heparin-induced thrombocytopenia
  • Splenectomy considerations
Adverse effects of drugs on the hematologic and lymphoreticular system
  • Antiplatelet drugs
  • Antithrombin drugs (dabigatran)
  • Chemotherapeutic agents
  • Inhibitors of coagulation factors
  • Methemoglobinemia
  • Propylthiouracil
  • Tumor lysis syndrome
  • Warfarin

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