Dehydroemetine

Dehydroemetine is used in the treatment of entamoeba histolytica and works by blocking chain elongation in protein synthesis by arresting the translocation of tRNA within the ribosome. Due to side effects other agents are preferred. Side effects include cardiotoxicity and neuromuscular weakness.

Class Drugs

• Dehydroemetine

Class Mechanism of Action

Blocks chain elongation in protein synthesis by arresting the translocation of tRNA within the ribosome 

Class Applications

Entamoeba histolytica

• Systemic

• Limited use due to other agents being better tolerated

Class Adverse Effects

Cardiotoxicity

Neuromuscular weakness

Drug Table

Drug Name	Application	Comments	Image
Dehydroemetine			"Dehydrator" "Emmet (Back to the Future)"