GI Stimulants

GI stimulants are used to stimulate gut contractility in patients with constipation.  These medications may induce diarrhea and can result in decreased absorption of other medications.  

Class Drugs

• Senna

• Bisacodyl

• Castor oil

Class Mechanism of Action

See individual drugs

Class Applications

Constipation

Class Adverse Effects

May decrease absorption of other drugs

Drug Table

Drug Name	Application	Comments	Image
Senna		Mechanism; -Stimulates peristalsis; -Increases bowel secretions	"Senator"
Bisacodyl		Mechanism; Stimulates nerves in colon to increase colon evacuation	"Bison" "Cuddle"
Castor Oil		Mechanism; -Metabolizes to ricinoleic acid; -Irritates intestinal lining; Adverse Effects; May cause uterine contractions, do not use in pregnancy	"Cast" "Oil"