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Catapult Pharmacology
Which of the following mechanisms of action pertain to penicillins?
A patient is brought to your clinic with concerns about spreading cellulitis. The patient was initiated on treatment with amoxicillin two days prior and has taken the prescription as directed, but the cellulitis continues to worsen. Which of the following is the most likely reason for treatment failure?
How does the antibiotic coverage compare between first and second generation cephalosporins?
A 65-year old male is ill with cellulitis that is found to be from MRSA. Which of the following cephalosporins would be an appropriate antibiotic choice?
Which broad spectrum cephalosporin has coverage against pseudomonas?
Which of the following third generation cephalosporins has coverage against pseudomonas aeruginosa?
What impact does an antibiotic binding to a penicillin binding protein cause?
You are treating a 67-year old patient with a urinary tract infection that has extended spectrum beta-lactamase? Which of the following drugs would be most appropriate?
A 34-year old with clostridium difficile diarrhea requires admission to the hospital. Which of the following antibiotics would be appropriate?
A 45-year old is being treated for cellulitis with vancomycin. The patient is receiving his first dose of the therapy and begins having a flushing rash to his face, neck, and upper torso. He is noted to be itchy. His vital signs are noted to be normal on recheck. Which of the following describes this phenomenon?
Which of the following mechanisms of action pertain to vancomycin?
A 31-year old is diagnosed with MRSA pneumonia. Which of the following antibiotics should be avoided?
Which of the following antibiotics has been shown to be associated with rhabdomyolysis.
You are working in the ICU and are discussing antibiotics for a critically ill patient who has failed multiple other antibiotic regimens for MRSA and VRE infections. The pharmacist suggests telavancin. What are possible side effects to consider?
You are treating a 56-year old female in the emergency department who is found to have a urinary tract infection. She does not require admission to the hospital. The patient has poor medication compliance and has had many return visits that have been secondary to not filling prescriptions. Which of the following medications would ensure treatment plan adherence?
Which of the following mechanisms of action pertain to fosfomycin?
A 41-year old presents with fever, joint aches, and a target-shaped rash after hiking in northern Minnesota. Which of the following medications would be most appropriate?
A 36-year old is diagnosed with "walking pneumonia" and has an allergy to azithromycin. What would be the next most appropriate oral therapy?
A 14-year old male is prescribed minocycline for treatment of acne. Which of the following would be appropriate advisement?
What do doxycycline and tigecycline share?
A 73-year old follows up with you in clinic after noticing hearing loss. Which of the following medication pairing would be most likely to contribute to hearing loss?
A 56-year old female with worsening fatigue, ptosis, difficulty swallowing, and double-vision that worsens as the day progresses is admitted to the hospital with endocarditis and is treated with ampicillin/sulbactam and gentamicin. You are called to the bedside as the patient has developed increased weakness of the extremities, difficulty breathing, worsening double vision. What condition does this patient have in addition to endocarditis?
A 56-year old female with worsening fatigue, ptosis, difficulty swallowing, and double-vision that worsens as the day progresses is admitted to the hospital with endocarditis and is treated with ampicillin/sulbactam and gentamicin. You are called to the bedside as the patient has developed increased weakness of the extremities, difficulty breathing, worsening double vision. What medications may reverse her condition?
A 32-year old with congenital long QT syndrome presents with pneumonia. Which of the following medications should be avoided?
What is the mechanism of action of fidaxomicin?
Which of the following medications causes grey baby syndrome
A 23-year old presents to the clinic with fever, abdominal pain, diarrhea one week after completing a course of clindamycin for cellulitis. They are found to have a WBC count of 23,000 /microL (Normal 4,500-11,000/microL). What is the likely cause?
Which of the following antibiotics should result in close monitoring for serotonin syndrome when co-administered with MAO inhibitors?
Which of the following medications is indicated for MRSA pneumonia?
A 43-year old presents to the emergency department with a Achille's tendon rupture. 1 month prior he was prescribed an antibiotic for sinusitis. What is the mechanism of the antibiotic that was most likely prescribed?
You have a patient with congenital prolonged QT interval who presents with 1 month of sinusitis symptoms, which have continued after several rounds of over the counter treatments. You decide to prescribe an antibiotic. Which is the safest choice?
Does levofloxacin cover pseudomonas infections?
Which of the following are known adverse effects of sulfonamides?
A 3-year old presents to your clinic with a burn to the left arm. Which of the following medications would be best to prescribe as a topical treatment?
An 83-year old with recurrent urinary tract infections on chronic suppressive therapy presents to your clinic with progressive shortness of breath and is diagnosed with pulmonary fibrosis. It was determined that the pulmonary fibrosis was likely caused by her long-term antibiotic. Which of the following antibiotics was the patient taking?
A 35-year old female presents to the clinic for concerns about vaginal discharge. She is found to have trichomonas and chlamydia infections. Which of the following treatments would be appropriate for treatment of trichomonas?
A 25-year old presents to the clinic with abdominal cramping and watery diarrhea one week after returning from a hiking trip. He did enjoy a drink from the mountain stream. Which of the following antibiotics would most likely be helpful?
A 45-year old is being treated for tuberculosis. He notices that his urine is red-orange color. Which of the following medications is a likely cause?
Which of the following medications inhibits arabinosyl transferase?
A 3-year old presents with status epilepticus. EMS gave several appropriate doses of lorazepam without improvement. They note that there was an empty bottle of isoniazid near the child. What medication should you administer to terminate the seizure?
Which of the following medications is useful in the treatment of leprosy?