Antifungals Quiz

A 4-year old female with chronic immune deficiency is hospitalized with a fungal infection in the intensive care unit. Prior antifungal regimens have been unsuccessful and amphotericin B is administered. What is the mechanism of this drug?

A 4-year old female with chronic immune deficiency is hospitalized with a fungal infection in the intensive care unit. Prior antifungal regimens have been unsuccessful and amphotericin B is administered. Which medication acts synergistically with amphotericin B?

Mutations in what enzyme may result in fungal resistance to triazoles?

A 64-year old on warfarin is diagnosed with histoplasmosis and is prescribed itraconazole. What side effects should you anticipate?

What is the mechanism of caspofungin?

A 16-year old soccer play presents with itchy feet. You notice a fungal rash and diagnose tinea pedis. Which of the following medications would be appropriate?

Which of the following medications inhibits squalene epoxidase?

A 34-year old is concerned about yellowing toenails. Which of the following medications would be an appropriate treatment?

Which of the following antifungal medications disrupts mitotic spindle formation?

Which of the following medications does not inhibit the C-14 α-demethylase enzyme?

What is tolnaftate used to treat?