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Catapult Pharmacology
A 12-year old presents 24 hours after developing fever, body aches, headache, cough, sore throat, and rhinorrhea. He is diagnosed with influenza A. Which of the following mechanisms is associated with an appropriate treatment?
Use of oseltamivir results in neuraminidase inhibition. What role does neuraminidase play in viral reproduction?
Which of the following drugs are indicated in the treatment of hepatitis B? (Check all that apply)
Adefovir is a nucleotide analog; entecavir is a nucleoside analog; and telbivudine is a thymidine analog. These medications all treat hepatitis B. What else do they have in common?
A 53-year old former IV drug user has hepatitis C. Which of the following medication - mechanism pairs would be an appropriate treatment?
A 38-year old with AIDS presents with retinitis. Viral PCR shows CMV as the cause. Which of the following drugs is most appropriate?
A 23-year old female presents to the clinic with a vaginal rash. You note vesicular lesions on her labia. PCR of the lesions is positive for HSV-2. Which of the following medications would be most appropriate?
Which of the following drugs are indicated in the treatment of CMV retinitis? (Check all that apply)
A 39-year old is diagnosed with CMV retinitis and is prescribed foscarnet. What is the mechanism of action of foscarnet?
A 24-year old is prescribed didanosine. Which of the following would be an expected adverse effect?
Which of the following drugs would be most likely to cause hepatotoxicity?
A 34-year old is being treated for an HIV infection and develops toxic epidermal necrolysis. Which of the following drugs would be most likely to have been prescribed?
A 65-year old male with a history of obesity, COPD, diabetes, high blood pressure, and high cholesterol presents 24 hours of cough and shortness of breath. He has normal vital signs and is diagnosed with COVID-19. Which of the following medications is indicated for treatment?
Do HIV protease inhibitors inhibit or induce the CYP450 system?
Which of the following medications binds to gp41 on HIV?
Which of the following medications binds to CCR5 on HIV?
Which of the following resistance mechanisms can develop to dolutegravir?