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Catapult Pharmacology
A 45-year-old female presents to the emergency department with swelling of the lower lip on the left side. She has a history of high blood pressure and high cholesterol. She sees a primary care clinician who prescribes medications to control her blood pressure and cholesterol. Which of the following medications is the most likely to cause the patient's presentation to the emergency department?
One of your patients is noted to have high blood pressure and you initiate lisinopril therapy. She has a history of diabetes. Your patient's blood pressure responds well to the treatment on a recheck in your clinic. After obtaining laboratory workup, you notice that your patient's GFR (glomerular filtration rate) decreased from 50 ml/min to 45 ml/min. Should you discontinue the therapy?
You have a 26-year-old female who has a history of hypertension and is now pursuing pregnancy. Which of the following medications would be most appropriate for blood pressure management?
You have admitted a 55-year-old male with a history of hypertension and hyperlipidemia to the hospital because of hyperkalemia. Which of the following medications should be held while in the hospital? (Choose all that apply)
A 67-year-old male presents to the emergency department after a syncopal event. His heart rate is 34. His blood pressure is normal. Which of the following medications would contribute to his syncopal event?
A 56-year-old female presents to clinic with new leg swelling. She takes hydrochlorothiazide, lisinopril and amlodipine for blood pressure. She takes metformin for diabetes. She has an echocardiogram performed, laboratory analysis, and ultrasound of her legs, which were all normal. Which of her medications is likely to be the cause of her leg swelling?
What is the mechanism of action of thiazide diuretics?
You have a patient who you would like to treat with a loop diuretic. He has a sulfa allergy. Which of the following medications would be most appropriate?
Which of the following medications have a stronger negative inotropic and chronotropic effects? (2 Correct Answers)
A 45-year-old male presents for follow up after a gout attack. Which of the following medications might you consider changing: hydrochlorothiazide, metoprolol, diltiazem, or aspirin?
Which of the following describes the mechanism of action for acetazolamide in the treatment of glaucoma?
A 57-year-old presents to the emergency department with nausea, vomiting, intermittent ventricular tachycardia, and findings of renal failure. While in the emergency department he is found to have an elevated digoxin level. What is the most appropriate treatment?
Which of the following is a known adverse effect of digoxin therapy?
Which of the following are known mechanisms of action of digoxin?
What is the mechanism of action of milrinone?
Which of the following are Class Ia antiarrhythmics?
Class I antiarrhythmics share this characteristic.
Sotalol has the following actions:
Which of the following tests should be monitored for toxicity from amiodarone?
A 64-year-old male presents to the clinic for routine follow up and notes that he has been feeling short of breath. You find that his pulmonary function tests indicate that he has restrictive lung disease and his chest x-ray shows findings of fibrotic lung disease. Which of the following medications should be discontinued immediately?
Adenosine is used in the treatment of paroxysmal supraventricular tachycardia. How are its effects mediated?
A 60-year-old presents to the emergency department with chest pain. She is given a dose of nitroglycerin and notes resolution of her discomfort. What is the primary mechanism that results in reduced anginal pain?
What is the mechanism of action of aspirin?
Which of the following medications irreversibly binds P2Y12 ADP receptors?
What is the mechanism of action of tirofiban?
What is the mechanism of the coronary steal phenomenon that can be seen with dipyridamole?
A 76-year-old male presents to you clinic with bilateral leg pain when he walks. The pain resolves when he rests. You find that he has peripheral vascular disease. Which of the following medications will help treat his intermittent claudication?
A 48-year-old female is admitted to the hospital after having a myocardial infarction and is on heparin anticoagulation via IV infusion. She develops shortness of breath and is found to have a pulmonary embolism? Laboratory analysis reveals a low platelet level. What is the next best step in management?
A 48-year-old female is admitted to the hospital after having a myocardial infarction and is on heparin anticoagulation via IV infusion. She suddenly develops a severe headache and is found to have an intracranial hemorrhage. Which medication will reverse the effects of heparin?
Dabigatran and argatroban share a mechanism of action. What is the shared mechanism of action?
Which of the following are a known side effect of coumadin?
You are initiating a patient on anticoagulation after diagnosing a deep vein thrombosis. Which of the following would be a benefit of using apixaban in comparison to coumadin?
A 75-year-old developed acute stroke symptoms and was treated with alteplase. Which of the following side-effects are important to monitor in the post-treatment phase?
Tranexamic acid has been found to be useful in treating a variety of conditions related to bleeding. What is the mechanism of action of tranexamic acid?
A 38-year-old is started on a medication to help control his hyperlipidemia and starts having muscle pains. Which of the following medications is a likely cause?
A 38-year-old is started on simvastatin for hyperlipidemia. He develops pain in his muscles. What is the next step in management?
You have a patient who has difficult to control hyperlipidemia and is currently taking niacin to supplement his statin use. He has been having trouble with symptoms of flushing. What can be done to improve this side-effect?
Which of the following medications for cholesterol treatment can be hepatotoxic?