Aromatase Inhibitors

Aromatase inhibitors are used in the treatment of hormone dependent breast cancers. Aromatase inhibitors work by decreasing the production of peripheral estrogen by inhibiting the aromatase enzyme. Hot flashes are a known side effect.

Class Drugs

• Anastrozole

• Letrozole

• Exemestane

Class Mechanism of Action

• Decreases the production of peripheral estrogen by inhibiting aromatase enzyme

Class Applications

• Treatment of hormone dependent breast cancer

Class Adverse Effects

• Hot flashes

Drug Table

Drug Name	Application	Comments	Image
Anastrozole			"Asteroid" "Hole"
Letrozole			"Latrine" "Ozone"
Exemestane			"Exam" "Mess"