Calcitonin

Calcitonin is a medication that is used in the treatment of osteoporosis, Paget's disease, and hypercalcemia. Calcitonin works by reducing the number and activity of osteoclasts, which reduces bone resorption.  Reduction of number and function of osteoclasts improves bone density and reduces serum calcium levels.  In addition, calcitonin reduces resorption of calcium in the renal tubules, which also reduces serum calcium levels.  Calcitonin can cause an increased risk of malignancy.

Class Drugs

• Calcitonin

Class Mechanism of Action

Inhibits osteoclast activity

Inhibits calcium resorption in the renal tubules

Class Applications

Osteoporosis

• Must be 5 years postmenopausal

Osteoporotic fracture pain control

Hypercalcemia

Paget's Disease

Class Adverse Effects

Increased risk of malignancy

Drug Table

Drug Name	Application	Comments	Image
Calcitonin			"Calcium Tablets" "Ink Toner"