Colchicine

Colchicine is a medication that is used in the treatment of acute gout flares and for treatment of pericarditis. Colchicine works by depolymerizing tubulin. Depolymerization of tubulin inhibits function of granulocytes and mobilization to affected areas.  GI side effects can be prominent. Blood dyscrasias can also occur. 

Class Drugs

• Colchicine

Class Mechanism of Action

Depolymerizes tubulin, which inhibits function of granulocytes and mobilization to affected areas

Class Applications

Treatment of pain in acute gout attacks

Pericarditis

Class Adverse Effects

GI effects

• Nausea, vomiting, abdominal pain, diarrhea

Neutropenia

Myopathy

Aplastic anemia

Contraindicated in pregnancy and breastfeeding

Drug Table

Drug Name	Application	Comments	Image
Colchicine			"Coal" "Chia" "Scene"