Dapsone

Dapsone treats both leprosy and pneumocystis jirovecii and works by inhibiting dihydropteroate synthetase, which decreases synthesis of folate.  Hemolytic anemia can occur in patients with glucose-6-phosphate dehydrogenase deficiency. Methemoglobinemia can also occur.  

Class Drugs

• Dapsone

Class Mechanism of Action

Inhibits dihydropteroate synthetase

• Decreases synthesis of folate

Bacteriostatic

Class Application

Leprosy

Pneumocystis jirovecii

Class Adverse Effects

Hemolytic anemia

• Encountered in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency

Methemoglobinemia

Peripheral neuropathy

Drug Table

Drug Name	Application	Comments	Image
Dapsone			"Dapper" "Sewn"