Entecavir

Entecavir is used in the treatment of hepatitis B. Entecavir is a nucleoside analog that works by competing for the viral reverse transcriptase, which inhibits all three steps of HBV polymerase: priming, transcription, and DNA synthesis. Nephrotoxicity is a possible side effect.

Class Drugs

• Entecavir

Class Mechanism of Action

Nucleoside analog that competes with natural nucleoside

• Inhibits transcription base priming

• Inhibits reverse transcription of mRNA

• Inhibits DNA synthesis

Class Applications

Hepatitis B

Class Adverse Effects

Nephrotoxicity

Drug Table

Drug Name	Application	Comments	Image
Entecavir			"Enter Sign" "Cave"