GI Lubricants

GI lubricants are another class of medication used for the treatment of constipation.  Mineral oil is ingested orally to produce its effect but can cause significant pneumonitis if aspirated. Glycerin suppositories are inserted rectally to assist passage of stool.  

Class Drugs

• Mineral Oil

• Glycerin suppositories

Class Mechanism of Action

Lubricates hard stool for easier passage

Class Applications

Constipation

Class Adverse Effects

See individual drugs

Drug Table

Drug Name	Application	Comments	Image
Mineral Oil		Adverse Effects; Avoid in patients at risk of aspiration as may cause pneumonitis	"Minerals" "Oil"
Glycerin Suppositories			"Glycerine - Bush"