Hepatitis C Virus Protease Inhibitors

Boceprevir and telaprevir are hepatitis C virus protease inhibitors. HCV protease inhibition limits viral replication. These medications are used in the treatment of hepatitis C. These medications are commonly used in combination with ribavirin or interferon as monotherapy results in rapid resistance.  

Class Drugs

• Boceprevir

• Telaprevir

Class Mechanism of Action

Inhibits HCV protease, limiting viral replication

Class Applications

Hepatitis C

• Used in combination with ribavirin or interferon

Class Adverse Effects

Anemia

Rapid resistance in monotherapy

Drug Table

Drug Name	Application	Comments	Image
Boceprevir			"Bocce Ball" "Preview"
Telaprevir			"Television" "Preview"