Neuraminidase Inhibitors

Neuraminidase is an enzyme found on the surface of the influenza virus and plays a role in viral budding. Oseltamivir and zanamivir work by inhibiting neuraminidase, which will reduce viral infectivity.  Neuraminidase inhibitors are used for treatment and prophylaxis of influenza infections. Resistance is common to these medications.  

Class Drugs

• Oseltamivir

• Zanamivir

Class Mechanism of Action

Inhibits neuraminidase

• Neuraminidase is an enzyme found on the surface of the virus and plays a role in viral budding

Class Applications

Influenza treatment

Influenza prophylaxis

Class Adverse Effects

Resistance

Drug Table

Drug Name	Application	Comments	Image
Oseltamivir			"Ossicle" "Tammy"
Zanamivir			"Tarzan" "Amy's Pizza"